Outcomes of HCV treatment: Who does well and who does not?

Molecular pathways: targeting hsp90--who benefits and who does not.

Many kinases and hormone receptors, important for cancer cell proliferation and survival, bind to and are dependent on the Hsp90 cycle for their folding and maturation. This provides the rationale for the development of small-molecule ATP competitors that, inhibiting Hsp90 function, lead to degradation of the "client" proteins. After continual efforts to improve the pharmacologic properties and...

How well is chronic pain managed? Who does it well?

BACKGROUND The variability in physician attitudes and goals for chronic pain relief and satisfaction with chronic pain management is unknown. OBJECTIVES To provide quantitative data regarding the status of chronic pain management by Michigan physicians. To relate physician's goals for pain management to physician confidence, preferences, and satisfaction with their chronic pain care. RESEAR...

Who does (not) benefit from entrepreneurship programs?

Funding information Social Sciences and Humanities Research Council of Canada; Centre for Innovation and Entrepreneurship at the Rotman School of Management, University of Toronto; SSHRC Research Summary: We evaluate a technology entrepreneurship training program by comparing career decisions among applicants accepted into the program with unaccepted applicants who are program finalists. We fin...

Who Does What: Taking Measures

[Who reads (but does not quote) Brazilian science].